← Human Trials & Peer-Reviewed Studies

Sex differences in the association of physical activity levels and vitamin D with obesity, sarcopenia, and sarcopenic obesity: a cross-sectional study.

Plain-language guide to PMID 36434519 (2022): clinical trial of Vitamin D, K2, Magnesium and Zinc in 3713 participants.

Key Facts

PMID
36434519
Journal
BMC geriatrics
Year
2022
Study type
Clinical Trial
Authors
Jia S et al. (8 authors)
DOI
10.1186/s12877-022-03577-4

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this clinical trial publication.

The researchers aimed to examine the sex differences in the relation between vitamin D status, PA levels, obesity and sarcopenia in community-dwelling middle-aged and older adults, as well as whether vitamin D status is a modifier in the relationship between PA and sarcopenia.

Multinomial logistic regression was performed to examine the relationship between PA, vitamin D and sarcopenia and obesity.

Why It Was Studied

The relationship between vitamin D and sarcopenia was inconsistent between men and women.

Physical activity (PA) may interact with vitamin D on sarcopenia.

Who Took Part

The study group was 3713 participants.

PubMed indexes the participants as middle-aged adults and older adults, both men and women.

A total of 3713 participants aged ≥ 50y were included in their study.

How the Study Was Run

The current study was a cross-sectional study based on the baseline survey of the West China Health and Aging Trend (WCHAT) study.

Sarcopenia was defined according to the Asian Working Group for Sarcopenia (AWGS) 2019 consensus.

Obesity was defined by body mass index (BMI) (≥ 28 kg/m2) and body fat mass percentage (≥ 60th percentile in each sex group). 25-hydroxyvitamin D was measured by chemiluminescent microparticle immunoassay and PA was evaluated by a validated China Leisure Time Physical Activity Questionnaire (CLTPAQ).

What Was Measured

Topics PubMed links to this paper include Cross-Sectional Studies, Exercise, Obesity, Sarcopenia, Sex Characteristics, Vitamin D and Vitamins.

Author keywords: Elderly, Sarcopenic obesity and WCHAT.

What This Means in Plain Language

This is a clinical trial of Vitamin D, K2, Magnesium and Zinc in 3713 participants.

With several hundred people or more, it is a fairly large study for this kind of research.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2022 (BMC geriatrics), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.