The effect of synbiotic and vitamin D co-supplementation on body composition and quality of life in middle-aged overweight and obese women: A randomized controlled trial.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Obesity is a worldwide problem which has involved large populations.

Since some dietary factors might modify obesity through various signaling pathways, the aim of this study was to investigate the effect of synbiotic plus vitamin D co-supplementation on body composition parameters and quality of life, in middle-aged overweight and obese women.

Who Took Part

According to the abstract, 88 women were involved.

PubMed indexes the participants as middle-aged adults, women only.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the women and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

At the beginning and at the end of the trial, anthropometric indices, body composition indicators, physical activity level, dietary intake, and quality of life score were measured by trained nutritionists.

Statistical analysis was performed with SPSS version 22.

What Was Measured

Topics PubMed links to this paper include Overweight, Vitamin D, Synbiotics, Quality of Life, Obesity, Body Composition and Vitamins.

The authors tagged it with the keywords Middle-aged women.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 88 women.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2022 (Clinical nutrition ESPEN), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.