Protocol for a randomised controlled trial to investigate the effects of vitamin K2 on recovery from muscle-damaging resistance exercise in young and older adults-the TAKEOVER study

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a clinical study.

Vitamin K2 supplementation has emerged as a potential candidate, and the aim of the current study, therefore, is to test the hypothesis that vitamin K2 supplementation can accelerate recovery, via modulation of the underlying physiological processes, following a bout of resistance exercise in young and older adults.

Why It Was Studied

Prospectively registered on 21 December 2020.

Who Took Part

By PubMed's age tags, the people studied were older adults.

How the Study Was Run

The design is described as randomized and placebo-controlled.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

The primary outcome is muscle strength with secondary outcomes including pain-free range of motion, functional abilities, surface electromyography (sEMG) and markers of inflammation and oxidative stress.

What Was Measured

PubMed files the paper under topics including Vitamin K 2, Resistance Training, Exercise, Muscle Strength, Muscle, Skeletal and Randomized Controlled Trials as Topic.

Author keywords: Inflammation, Muscle damage, Recovery and Resistance exercise.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 2 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2022 (Trials), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.