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Randomized clinical trial to evaluate the effect on postprandial glycemia of Nutren Control®, a glycemia-targeted specialized supplement, compared to standardized breakfast in patients with type-2 diabetes: the CONTROL DIABETES study.
Plain-language guide to PMID 36602126 (2023): crossover randomized controlled trial of Copper (Supplement).
Key Facts
- PMID
- 36602126
- Journal
- Nutricion hospitalaria
- Year
- 2023
- Study type
- Randomized Controlled Trial
- Authors
- Zagury RL et al. (8 authors)
- DOI
- 10.20960/nh.04204
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Copper (Supplement), published as a randomized controlled trial.
Objective: to evaluate the effects of a new glycemia targeted specialized supplement (GTSS) compared to a standard breakfast on postprandial blood glucose (PPG).
Why It Was Studied
The standardized breakfast was isoenergetic compared to the GTSS, differing on macronutrients distribution.
Intermittent scanning continuous glucose monitoring system (isCGM) determined the difference between the interventions regarding the incremental area under the curve (iAUC) of the PPG (3 hours after intervention), as a primary endpoint; secondary endpoints were the difference between the interventions regarding the glycemic peak, postprandial glucose excursion (PPGE), mean blood glucose (MBG) and time in range (TIR).
Who Took Part
The age groups tagged for this paper are adults, middle-aged adults and older adults.
How the Study Was Run
In design terms this was a randomized and crossover study.
The participants were allocated by chance, so the Copper (Supplement) group and the comparison group should start out alike.
Each person switched between Copper (Supplement) and the comparison at some point, usually with a gap in between.
What Was Measured
Intermittent scanning continuous glucose monitoring system (isCGM) determined the difference between the interventions regarding the incremental area under the curve (iAUC) of the PPG (3 hours after intervention), as a primary endpoint; secondary endpoints were the difference between the interventions regarding the glycemic peak, postprandial glucose excursion (PPGE), mean blood glucose (MBG) and time in range (TIR).
PubMed files the paper under topics including Diabetes Mellitus, Type 2, Blood Glucose, Breakfast, Blood Glucose Self-Monitoring, Glucose, Postprandial Period and Insulin.
The authors tagged it with the keywords Suplemento dietético. Glucosa sanguínea. Período posprandial. Diabetes mellitus de tipo 2. Nutrimentos.
What This Means in Plain Language
The paper is a randomized and crossover study of Copper (Supplement).
The publication is from 2023 (Nutricion hospitalaria), a journal based in Spain.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.