Continued versus discontinued oxytocin stimulation in the active phase of induced labour: Factors associated with unexpectedly high rates of conversion to open label oxytocin in the CONDISOX trial

What Was Tested

This randomized controlled trial paper looks at Oxytocin.

1200 women having labour induced.

Who Took Part

The abstract describes 1200 women taking part.

PubMed tags the participants as women only.

Analysis of outcomes by actual management.

How the Study Was Run

The researchers set it up as a randomized and open-label study.

Because people in this Oxytocin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Everyone knew when Oxytocin was being given (open label), which is simpler to run but leaves more room for expectations to affect what is reported.

Secondary retrospective analysis of data from a prospective randomised controlled trial.

Nine hospitals in Denmark and one in the Netherlands between 8 April 2016 and 30 June 2020.

What Was Measured

The subject headings attached to it are Oxytocin, Oxytocics, Cesarean Section and Labor, Induced.

Author keywords: caesarean section, induction of labour and oxytocin infusion.

What This Means in Plain Language

The paper is a randomized and open-label study of Oxytocin in 1200 women.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2023 (BJOG : an international journal of obstetrics and gynaecology), a journal based in England.

More context: the Oxytocin compound page, all human trials.