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Lesion sterilization and tissue repair with chloramphenicol, tetracyline, zinc oxide/eugenol paste versus conventional pulpectomy: A 36-month randomized controlled trial.

Plain-language guide to PMID 36719000 (2023): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 70 children.

Key Facts

PMID
36719000
Journal
International journal of paediatric dentistry
Year
2023
Study type
Randomized Controlled Trial
Authors
Castro M et al. (6 authors)
DOI
10.1111/ipd.13056

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Endodontic treatment of primary molars represents one of the challenges in pediatric dentistry.

There is a lack of consensus in the literature about the endodontic techniques and filling paste for primary teeth with pulp necrosis.

Who Took Part

The study group was 70 children.

PubMed indexes the participants as young children and children.

Eighty-eight primary molars with pulp necrosis from 70 children between the ages of 3 and 8 years were included.

How the Study Was Run

The design is described as randomized.

The children were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

The teeth were randomized to the LSTR with CTZ paste group or pulpectomy with ZOE paste group.

Clinical and radiographic evaluations were performed at 18, 24, 30 and 36 months.

What Was Measured

Endodontic treatment of primary molars represents one of the challenges in pediatric dentistry.

There is a lack of consensus in the literature about the endodontic techniques and filling paste for primary teeth with pulp necrosis.

Topics PubMed links to this paper include Eugenol, Chloramphenicol, Pulpectomy, Zinc Oxide, Dental Pulp Necrosis, Zinc Oxide-Eugenol Cement and Sterilization.

Author keywords: LSTR therapy, primary molars and randomized controlled trial.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 70 children.

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2023 (International journal of paediatric dentistry), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.