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Effect of Vitamin D Supplementation on Depression in Adults: A Systematic Review of Randomized Controlled Trials (RCTs).

Plain-language guide to PMID 36839310 (2023): systematic review of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

Key Facts

PMID
36839310
Journal
Nutrients
Year
2023
Study type
Systematic Review
Authors
Guzek D et al. (6 authors)
DOI
10.3390/nu15040951

What This Paper Covers, in Plain Language

What It Covers

This systematic review looks at Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

The study aimed to carry out a systematic review of the studies assessing the influence of vitamin D supplementation on depression within Randomized Controlled Trials (RCTs).

The systematic review was prepared on the basis of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and was registered in the International Prospective Register of Systematic Reviews (PROSPERO) database (CRD42020155779).

Who the Included Studies Covered

The age groups tagged for this paper are adults, women only.

How the Review Was Done

The number of screened records was 8514, and 8 records were included.

What Was Measured

The study aimed to carry out a systematic review of the studies assessing the influence of vitamin D supplementation on depression within Randomized Controlled Trials (RCTs).

Two independent researchers conducted screening, including, reporting, and risk of bias assessment using the revised Cochrane risk-of-bias tool for randomized trials.

PubMed files the paper under topics including Dietary Supplements, Randomized Controlled Trials as Topic, Vitamin D, Vitamins and Vitamin D Deficiency.

Author keywords: Randomized Controlled Trials (RCTs), depression, depressive symptoms, diet therapy, major depressive disorder and supplementation.

What This Means in Plain Language

This is a systematic review of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

The publication is from 2023 (Nutrients), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.

Our Notes on the Compounds

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.