Vitamin D3 supplementation as an adjunct in the management of childhood infectious diarrhea: a systematic review.

What It Covers

Researchers studied Vitamin D, K2, Magnesium and Zinc in this systematic review publication.

The researchers estimated the I2 and tau2 values to assess between-study heterogeneity.

Why It Was Studied

Some studies have reported the possible role of vitamin D3 in ameliorating disease outcomes in childhood infectious diarrhea.

Who the Included Studies Covered

The researchers selected primary studies that met the review's inclusion criteria, screened their titles and abstracts, and removed duplicates.

The researchers conducted a quality assessment of randomized controlled trials (RCTs) and non-randomized studies with the Cochrane collaboration tool and the Newcastle Ottawa Scale, respectively.

How the Review Was Done

The researchers searched the PubMed and Google Scholar electronic databases for relevant articles without limiting their year of publication.

The researchers extracted data items from selected studies using a structured data-extraction form.

The researchers assessed the strength of the relationship between serum vitamin D levels and diarrhea using the correlation model.

What Was Measured

Some studies have reported the possible role of vitamin D3 in ameliorating disease outcomes in childhood infectious diarrhea.

Topics PubMed links to this paper include Cholecalciferol, Vitamin D, Vitamins, Dysentery, Diarrhea and Dietary Supplements.

The authors tagged it with the keywords Adjunct therapy, Childhood, Infectious diarrhea and Innate immunity.

What This Means in Plain Language

This is a systematic review of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 8 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2023 (BMC infectious diseases), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.