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Branched-chain amino acids plus vitamin D supplementation promote increased muscle strength following lumbar surgery for lumbar spinal stenosis: a randomized trial.

Plain-language guide to PMID 36940921 (2023): single-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
36940921
Journal
The spine journal : official journal of the North American Spine Society
Year
2023
Study type
Randomized Controlled Trial
Authors
Minetama M et al. (12 authors)
DOI
10.1016/j.spinee.2023.03.007

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Adequate nutrition is essential to address the surgical stress response and mitigate loss of muscle mass, strength, and functionality in older adults with lumbar spinal stenosis (LSS).

Who Took Part

By PubMed's age tags, the people studied were older adults.

Eighty patients who received lumbar surgery for LSS.

How the Study Was Run

The design is described as randomized and single-blind.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Only one side, usually the participants, was kept unaware of whether Vitamin D, K2, Magnesium and Zinc was given.

A single-center, single-blind randomized controlled trial.

What Was Measured

PubMed files the paper under topics including Spinal Stenosis, Amino Acids, Branched-Chain, Vitamin D, Muscle Strength, Intermittent Claudication and Dietary Supplements.

Author keywords: Amino acids, Branched-chain amino acids, Lumbar spinal stenosis, Muscle mass, Nutrition, Physical therapy and Protein.

What This Means in Plain Language

The paper is a randomized and single-blind study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2023 (The spine journal : official journal of the North American Spine Society), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.