Assessment of the relationship between vitamin D with semen analysis parameters and reproductive hormones levels before and after kidney transplantation: An Iranian randomized and double-blinded study.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

This study aimed to figure out the effect of serum vitamin D levels on semen analysis parameters and reproductive hormones before and after renal transplantation in ESRD patients.

Why It Was Studied

Vitamin D's role is noticeable on homeostasis of calcium and phosphorous and bone mineralization.

Some studies prove that vitamin D has a role in reproductive pathways in male and females and its direct relationship with serum androgen levels in males.

Who Took Part

PubMed indexes the participants as young adults, adults and middle-aged adults, both men and women.

Participants were divided into two groups randomly.

Vitamin D levels, LH, FSH, creatinine, glomerular filtration rate (GFR), calcium, total and free testosterone, PTH, sexual function, and semen analysis parameters were evaluated in a determined interval before and after (three and 6 months) kidney transplantation.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

This double-blind randomized clinical trial was carried out on 70 ESRD males (21-48 years old) who were candidates for renal transplantation at Sina hospital between 2021 and 2022.

What Was Measured

Some studies prove that vitamin D has a role in reproductive pathways in male and females and its direct relationship with serum androgen levels in males.

PubMed files the paper under topics including Vitamin D, Iran, Kidney Transplantation, Infertility, Male, Sperm Count, Calcium and Creatinine.

Author keywords: CKD, Semen analysis and renal transplantation.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2023 (Urologia), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.