Comparative Analysis of Solifenacin Plus Desmopressin Versus Desmopressin Alone in the Treatment of Primary Mono Symptomatic Nocturnal Enuresis

What Was Tested

Researchers studied Vasopressin and Desmopressin in this randomized controlled trial publication.

Who Took Part

The study group was 88 children.

The age groups tagged for this paper are young children, children and teenagers.

A total of 88 children, 5-14 years old, diagnosed with PMNE were enrolled in this randomized control trial (RCT) from June 2017 to June 2020.

After informed written consent patients were randomized to one of the two therapeutic groups.

How the Study Was Run

The researchers set it up as a randomized study.

Because people in this Vasopressin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The timeline in the abstract includes three months.

Group 1 received one puff of desmopressin nasal spray 1 h before bedtime every night.

All patients were evaluated after three months for their response to treatment and drug side effects.

What Was Measured

The subject headings attached to it are Deamino Arginine Vasopressin, Nocturnal Enuresis, Solifenacin Succinate and Nasal Sprays.

The authors tagged it with the keywords Desmopressin and PMNE.

What This Means in Plain Language

The paper is a randomized study of Vasopressin and Desmopressin in 88 children over three months.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2023 (Journal of pediatric surgery), a journal based in United States.

More context: the Vasopressin compound page and the Desmopressin compound page, all human trials.