The effect of pregnancy vitamin D supplementation on offspring bone mineral density in childhood: a systematic review and meta-analysis.

What It Covers

Researchers studied Vitamin D, K2, Magnesium and Zinc in this meta-analysis publication.

A systematic review and meta-analysis was performed to assess the effect of pregnancy vitamin D supplementation on offspring bone mineral density (BMD) in childhood.

Who the Included Studies Covered

The age groups tagged for this paper are young children and children, women only.

A literature search was conducted for published RCTs of antenatal vitamin D supplementation with assessment of offspring BMD or bone mineral content (BMC) by dual-energy X-ray absorptiometry (DXA) using MEDLINE and EMBASE up to 13th July 2022.

Study findings were grouped in two age groups of offspring assessment: neonatal period and early childhood (3-6 years).

How the Review Was Done

Risk of bias was assessed using the Cochrane Risk of Bias 2 tool.

What Was Measured

PubMed files the paper under topics including Vitamin D, Bone Density, Vitamins, Cholecalciferol, Dietary Supplements and Randomized Controlled Trials as Topic.

Author keywords: BMD, Epidemiology, Osteoporosis, Pregnancy and RCT.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 9 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2023 (Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.