Relationship between Vitamin D and Immunity in Older People with COVID-19.

What It Covers

Researchers studied Vitamin D, K2, Magnesium and Zinc in this review publication.

Vitamin D is a group of lipophilic hormones with pleiotropic actions.

In the pandemic era, by considering the response of the different branches of the immune system to SARS-CoV-2 infection, their aims are both to analyse, among the pleiotropic effects of vitamin D, how its strong multimodal modulatory effect on the immune system is able to affect the pathophysiology of COVID-19 disease and to emphasise a possible relationship between the well-known circannual fluctuations in blood levels of this hormone and the epidemiological trend of this infection, particularly in the elderly population.

Who the Included Studies Covered

By PubMed's age tags, the people studied were older adults.

What Was Measured

In the pandemic era, by considering the response of the different branches of the immune system to SARS-CoV-2 infection, their aims are both to analyse, among the pleiotropic effects of vitamin D, how its strong multimodal modulatory effect on the immune system is able to affect the pathophysiology of COVID-19 disease and to emphasise a possible relationship between the well-known circannual fluctuations in blood levels of this hormone and the epidemiological trend of this infection, particularly in the elderly population.

Calcifediol levels have been found to be inversely correlated with upper respiratory tract infections in several studies, and this activity seems to be related to its role in the innate immunity.

PubMed files the paper under topics including Vitamin D, COVID-19, Calcifediol, SARS-CoV-2 and Vitamins.

The authors tagged it with the keywords U-shape and infections.

What This Means in Plain Language

This is a review of Vitamin D, K2, Magnesium and Zinc.

The publication is from 2023 (International journal of environmental research and public health), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.