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Efficacy of methylene blue and curcumin mediated antimicrobial photodynamic therapy in the treatment of indirect pulp capping in permanent molar teeth
Plain-language guide to PMID 37150490 (2023): randomized controlled trial study of Methylene blue (non-peptide stack partner).
Key Facts
- PMID
- 37150490
- Journal
- Photodiagnosis and photodynamic therapy
- Year
- 2023
- Study type
- Randomized Controlled Trial
- Authors
- AlSunbul H et al. (2 authors)
- DOI
- 10.1016/j.pdpdt.2023.103598
What This Study Did, in Plain Language
What Was Tested
Researchers studied Methylene blue (non-peptide stack partner) in this randomized controlled trial publication.
Who Took Part
All specimens were embedded in polyvinyl cross-sections to the cemento-enamel junction.
After disinfection methods, the universal adhesive was used, and all specimens were restored using giomer.
How the Study Was Run
The design is described as randomized.
The participants were allocated by chance, so the Methylene blue (non-peptide stack partner) group and the comparison group should start out alike.
One Hundred grossly carious human permanent molars were collected through non-traumatic extraction.
The cavity preparation was conducted by grinding the samples using silicon carbide discs.
After culturing Streptococcus mutans (S. mutans), a 10 µL of S. mutans suspension (106 colony forming units/mL) was transferred in each tooth cavity and anaerobically incubated for 48 h at 37 °C.
Eventually, confocal laser scanning microscopy, shear bond strength (SBS), micro-tensile bond strength (μTBS), four-point bending strength (4P-BS) analyses were performed, and the data were analyzed statistically.
What Was Measured
Topics PubMed links to this paper include Anti-Bacterial Agents, Anti-Infective Agents, Biofilms, Curcumin, Dental Pulp Capping, Disinfectants and Methylene Blue.
The authors tagged it with the keywords Chlorhexidine, Disinfection, Photodynamic therapy, Photosensitizing agents and Sodium hypochlorite.
What This Means in Plain Language
The paper is a randomized study of Methylene blue (non-peptide stack partner).
Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2023 (Photodiagnosis and photodynamic therapy), a journal based in Netherlands.
More context: the Methylene blue (non-peptide stack partner) compound page, all human trials.
Our Notes on the Compound
Methylene blue (non-peptide stack partner): Described as an electron cycler, not just a dye.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.