Association of vitamin D in individuals with periodontitis: an updated systematic review and meta-analysis.

What It Covers

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a meta-analysis.

The purpose of this Meta-analysis is twofold: (1) compare vitamin D levels in individuals with or without periodontitis; (2) assess the effects of vitamin D supplementation during scaling and root planing (SRP) on periodontal clinical parameters in individuals with periodontitis.

The Cochrane Collaboration Risk of bias (ROB) assessment tool, the risk of bias in non-randomized studies of intervention (ROBINS-I) tool, the Newcastle-Ottawa Quality Assessment Scale (NOS), and Agency for Healthcare Quality and Research (AHRQ) were used to evaluate randomized controlled trial (RCT), non-RCT, case-control study, and cross-sectional study, respectively.

Why It Was Studied

There are differences in vitamin D levels between periodontitis and healthy individuals, but the effect of vitamin D on periodontitis is controversial.

How the Review Was Done

A systematic search was conducted in five databases (PubMed, Web of Science, MEDLINE, EMBASE, and Cochrane library), published from the database inception to 12 September 2022.

What Was Measured

There are differences in vitamin D levels between periodontitis and healthy individuals, but the effect of vitamin D on periodontitis is controversial.

The subject headings attached to it are Dental Scaling, Periodontal Diseases, Periodontitis, Root Planing, Vitamin D and Clinical Trials as Topic.

Author keywords: 25(OH)D, Meta-analysis and Scaling and root planning.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2023 (BMC oral health), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.