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Vitamin B12 supplementation improves cognitive function in middle aged and elderly patients with cognitive impairment
Plain-language guide to PMID 37334792 (2023): randomized controlled trial study of Cyanocobalamin (Vitamin B12) in 2021, participants.
Key Facts
- PMID
- 37334792
- Journal
- Nutricion hospitalaria
- Year
- 2023
- Study type
- Randomized Controlled Trial
- Authors
- Zhou L et al. (5 authors)
- DOI
- 10.20960/nh.04394
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Cyanocobalamin (Vitamin B12), published as a randomized controlled trial.
Objectives: to determine the effects of vitamin B12 supplementation on neuropsychological function and disease progression in middle aged and elderly patients with cognitive impairment.
Why It Was Studied
Methods: this was a prospective case-control study.
Demographic characteristics and blood biochemical variables were obtained from all participants.
Who Took Part
According to the abstract, 2021, participants were involved.
The age groups tagged for this paper are middle-aged adults and older adults.
From May 2020 to May 2021, 307 participants clinically diagnosed with cognitive impairment in the Department of Neurology of the First Affiliated Hospital of Chongqing Medical University were enrolled.
A total of 115 patients were included in this study.
How the Study Was Run
The design is described as randomized.
Because people in this Cyanocobalamin (Vitamin B12) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
What Was Measured
The subject headings attached to it are Case-Control Studies, Cognitive Dysfunction, Vitamin B 12, Cognition, Vitamins, Vitamin D and Dietary Supplements.
The authors tagged it with the keywords Vitamina B12. Cobalamina. Deterioro cognitivo. Mediana edad y ancianos. Función frontal..
What This Means in Plain Language
The paper is a randomized study of Cyanocobalamin (Vitamin B12) in 2021, participants.
With several hundred people or more, it is a fairly large study for this kind of research.
The publication is from 2023 (Nutricion hospitalaria), a journal based in Spain.
More context: the Cyanocobalamin (Vitamin B12) compound page, all human trials.
Our Notes on the Compound
Cyanocobalamin (Vitamin B12): A synthetic form of vitamin B12 (cobalamin), an essential nutrient for DNA synthesis, red blood cell formation and neurological function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.