Glycaemic and insulinaemic impact of a diabetes-specific oral nutritional supplement with extra-virgin olive oil in patients with type 2 diabetes mellitus at nutritional risk: a randomized, double-blind, crossover, multicentre clinical trial (DIACARE).

What Was Tested

The paper reports a study of Copper (Supplement), published as a randomized controlled trial.

Objective: the aim of the study was to compare the glycaemic and insulinaemic response of patients with type 2 diabetes at risk of malnutrition after oral feed between a diabetes-specific formula with AOVE (DSF) and a standard one (STF).

Why It Was Studied

Introduction: there is controversy about the usefulness of specific enteral nutrition formulas in malnourished patients with diabetes.

The effects on blood glucose and other aspects of metabolic control are not fully understood in the scientific literature.

Who Took Part

According to the abstract, 180 patients were involved.

PubMed indexes the participants as children, both men and women.

The patients were randomized to receive either DSF or STF, a week apart.

How the Study Was Run

The design is described as randomized, double-blind, crossover and multicenter.

Because people in this Copper (Supplement) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Copper (Supplement) study, the assignments were hidden from both participants and investigators until the end.

In the crossover set-up each of the patients took both Copper (Supplement) and the comparison in turn, acting as their own control.

More than one site took part, so the patients came from several places.

What Was Measured

PubMed files the paper under topics including Diabetes Mellitus, Type 2, Olive Oil, Blood Glucose, Insulin and Malnutrition.

The authors tagged it with the keywords Diabetes mellitus tipo 2. Desnutrición relacionada con la enfermedad. Aceite de oliva virgen extra. Glucemia posprandial. Insulinemia posprandial. Glucosa intersticial.

What This Means in Plain Language

The paper is a randomized, double-blind and crossover study of Copper (Supplement) in 180 patients.

The publication is from 2023 (Nutricion hospitalaria), a journal based in Spain.

More context: the Copper (Supplement) compound page, all human trials.