Effects of intravenous administration of magnesium sulfate in propofol-based sedation for ERCP in elderly patients: a randomized, double-blind, placebo-controlled study.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Propofol-based sedations are widely used in elderly patients for endoscopic retrograde cholangiopancreatography (ERCP) procedure, but respiratory depression and cardiovascular adverse events commonly occur.

Who Took Part

The age groups tagged for this paper are older adults.

Eighty patients aged from 65 to 79 years who were scheduled for ERCP were enrolled.

Total propofol requirement during ERCP was the primary outcome.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

Intraoperative sedation was provided by propofol.

What Was Measured

PubMed files the paper under topics including Propofol, Hypnotics and Sedatives, Cholangiopancreatography, Endoscopic Retrograde, Magnesium Sulfate, Magnesium, Pain and Administration, Intravenous.

The authors tagged it with the keywords Elderly patients, Endoscopic retrograde cholangiopancreatography, Intravenous magnesium and Sedation.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2023 (BMC geriatrics), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.