U-shaped association of serum magnesium with mild cognitive impairment among hemodialysis patients: a multicenter study.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this observational study publication.

This study aimed to evaluate the association between serum magnesium levels and mild cognitive impairment among HD patients.

Why It Was Studied

The optimal serum magnesium level of patients undergoing hemodialysis (HD) with cognitive impairment is still unclear.

Who Took Part

The age groups tagged for this paper are middle-aged adults, both men and women.

Patients undergoing hemodialysis from 22 dialysis centers in Guizhou Province, China were recruited into the study.

HD patients were divided into five groups according to serum magnesium quintile.

How the Study Was Run

In design terms this was a multicenter study.

More than one site took part, so the participants came from several places.

This was a multicenter observational study.

Cognitive function was measured with Mini Mental State Examination.

The outcome was an incident mild cognitive impairment (MCI).

Multivariate logistic regression analysis, restricted cubic spline and subgroup analysis were applied to explore the association of serum magnesium level with MCI.

What Was Measured

The optimal serum magnesium level of patients undergoing hemodialysis (HD) with cognitive impairment is still unclear.

The subject headings attached to it are Magnesium, Cognitive Dysfunction, Renal Dialysis, Hypertension and China.

Author keywords: U-shaped relationship, hemodialysis and mild cognitive impairment.

What This Means in Plain Language

The paper is a multicenter study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 9 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2023 (Renal failure), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.