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The effect of vitamin D supplementation on the brain mapping and behavioral performance of children with ADHD: a double-blinded randomized controlled trials.

Plain-language guide to PMID 37489917 (2024): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
37489917
Journal
Nutritional neuroscience
Year
2024
Study type
Randomized Controlled Trial
Authors
Mirhosseini H et al. (5 authors)
DOI
10.1080/1028415X.2023.2233752

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

This study aimed to investigate the concomitant effects of Vitamin D3 supplementation and Neurofeedback on children with ADHD.

Why It Was Studied

Attention deficit hyperactivity disorder (ADHD) is one of the common neurodevelopmental diseases that are accompanied with EEG pattern changes and Low levels of 25-hydroxyvitamin D [25(OH)D].

Neurofeedback provides a feedback signal to alleviate brain wave abnormalities and offers an alternative therapy for ADHD.

Who Took Part

The age groups tagged for this paper are children, both men and women.

This study was implemented on children with an established diagnosis of ADHD who received multisession Neurofeedback therapy.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

The background rhythm was measured using quantitative EEG both before and at the end duration of the therapy.

What Was Measured

Attention deficit hyperactivity disorder (ADHD) is one of the common neurodevelopmental diseases that are accompanied with EEG pattern changes and Low levels of 25-hydroxyvitamin D [25(OH)D].

Topics PubMed links to this paper include Attention Deficit Disorder with Hyperactivity, Dietary Supplements, Neurofeedback, Vitamin D, Brain, Electroencephalography and Cholecalciferol.

Author keywords: ADHD, Brain mapping, Mental health, VDRs, theta/ alpha ratio and theta/ beta ratio.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 5 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2024 (Nutritional neuroscience), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.