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The association of vitamin D with bone microarchitecture, muscle strength, and mobility performance in older women in long-term care.
Plain-language guide to PMID 37544395 (2023): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 246 women.
Key Facts
- PMID
- 37544395
- Journal
- Bone
- Year
- 2023
- Study type
- Randomized Controlled Trial
- Authors
- Haeri NS et al. (3 authors)
- DOI
- 10.1016/j.bone.2023.116867
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
Trabecular bone score (TBS) is a novel method to evaluate bone microarchitecture, whereas grip strength and gait speed are simple methods to assess muscle strength and function.
The researchers sought to investigate this relationship in older women with osteoporosis and multiple comorbid conditions residing in long-term care (LTC) facilities.
Why It Was Studied
Osteoporosis and sarcopenia are prevalent in older adults.
Few studies have linked the relationship between vitamin D levels (25OHD) with TBS, grip strength, and gait speed in healthy community dwelling adults.
Who Took Part
The abstract describes 246 women taking part.
PubMed indexes the participants as older adults and people over 80, women only.
The researchers analyzed baseline 25OHD, spine TBS, grip strength, and gait speed in 246 women with osteoporosis who were residents of LTC and enrolled in a randomized controlled clinical trial.
How the Study Was Run
The design is described as randomized.
The women were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
What Was Measured
Few studies have linked the relationship between vitamin D levels (25OHD) with TBS, grip strength, and gait speed in healthy community dwelling adults.
Topics PubMed links to this paper include Vitamin D, Bone Density, Long-Term Care, Muscle Strength, Osteoporosis, Vitamins and Hand Strength.
The authors tagged it with the keywords 25-Hydroxy vitamin D, Bone microarchitecture and Physical performance.
What This Means in Plain Language
The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 246 women.
Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2023 (Bone), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.