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The Effect of Zinc Biofortified Wheat Produced via Foliar Application on Zinc Status: A Randomized, Controlled Trial in Indian Children.

Plain-language guide to PMID 37633331 (2023): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
37633331
Journal
The Journal of nutrition
Year
2023
Study type
Randomized Controlled Trial
Authors
Signorell C et al. (8 authors)
DOI
10.1016/j.tjnut.2023.08.013
Registered trial
NCT02241330

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

To assess the effect of agronomically biofortified whole wheat flour (BFW) on plasma zinc (PZC) compared with a postharvest fortified wheat (PHFW) and unfortified control wheat (CW) when integrated in a midday school meal scheme.

Who Took Part

By PubMed's age tags, the people studied were young children and children, both men and women.

Measurements of anthropometry, blood biochemistry, and leukocyte DNA strand breaks were conducted.

How the Study Was Run

The design is described as randomized and double-blind.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

The researchers applied sparse serial sampling to monitor PZC over time, and analysis was performed using linear mixed-effects models.

What Was Measured

Topics PubMed links to this paper include Zinc, Triticum, Food, Fortified, Biofortification, India, Nutritional Status and Flour.

The authors tagged it with the keywords DNA strand breaks, plasma zinc, school-age children, wheat and zinc deficiency.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2023 (The Journal of nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.