The effect of vitamin B12 on idiopathic tinnitus

What Was Tested

Researchers studied Cyanocobalamin (Vitamin B12) in the context of tinnitus in this randomized controlled trial publication.

The aim of this study was to evaluate the effect of vitamin B12 on idiopathic tinnitus.

Why It Was Studied

Tinnitus is one of the most important challenges in the field of ear, nose and throat diseases.

Who Took Part

The study group was 140 patients.

PubMed tags the participants as both men and women.

In this double-blind clinical trial study, 140 patients with idiopathic tinnitus were divided into two groups, the group receiving vitamin B12 and the group receiving placebo.

All patients filled a THI questionnaire before the participation, one month and three months after the participation.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Because people in this Cyanocobalamin (Vitamin B12) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Cyanocobalamin (Vitamin B12) study, the assignments were hidden from both participants and investigators until the end.

The comparison arm used a placebo, so changes seen with Cyanocobalamin (Vitamin B12) could be set against what happens without it.

The first group received vitamin B12 for a month and the other group received placebo.

VAS evaluation questionnaires were also filled for the patients before the participation, one month and three months after the participation.

The effect of vitamin B12 on tinnitus was also assessed according to hearing loss status.

The two groups were also compared regarding the side effects.

What Was Measured

Topics PubMed links to this paper include Tinnitus, Vitamin B 12, Hearing Loss and Deafness.

The authors tagged it with the keywords THI, VAS and Vitamin B12.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Cyanocobalamin (Vitamin B12) in 140 patients in people with tinnitus.

The abstract goes on to report its results in about 9 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2024 (American journal of otolaryngology), a journal based in United States.

More context: the Cyanocobalamin (Vitamin B12) compound page, Tinnitus research.