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Effectiveness of tubular coaxial nickel-titanium and copper nickel-titanium orthodontic aligning archwires: A randomized clinical trial.
Plain-language guide to PMID 37776695 (2023): parallel-group randomized controlled trial of Copper (Supplement).
Key Facts
- PMID
- 37776695
- Journal
- International orthodontics
- Year
- 2023
- Study type
- Randomized Controlled Trial
- Authors
- Noori RM et al. (2 authors)
- DOI
- 10.1016/j.ortho.2023.100812
- Registered trial
- NCT05391542
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Copper (Supplement), published as a randomized controlled trial.
This study aimed to compare tubular coaxial-NiTi and copper-NiTi orthodontic aligning archwires in terms of teeth alignment, patients' pain perception, and root resorption.
Why It Was Studied
The trial was registered in ClinicalTrials.gov on 26/05/2022 with a registration ID: NCT05391542, https://clinicaltrials.gov/ct2/show/NCT05391542.
Who Took Part
PubMed indexes the participants as teenagers.
Orthodontic patients aged 12 years or older, having Little's irregularity index (LII) of 5-9mm were randomly allocated to either the copper-NiTi group or tubular coaxial-NiTi group with a 1:1 allocation ratio.
How the Study Was Run
In design terms this was a randomized and parallel-group study.
The participants were allocated by chance, so the Copper (Supplement) group and the comparison group should start out alike.
Groups ran in parallel: each of the participants stayed in one arm throughout.
The archwire sequence was 0.014-inch followed by 0.018-inch for the copper-NiTi group and 0.016-inch followed by 0.018-inch for the tubular coaxial-NiTi group.
Evaluation of pain perception was performed using a visual analog scale (VAS) during the first week following each archwire insertion.
What Was Measured
PubMed files the paper under topics including Copper, Dental Alloys, Nickel, Titanium, Root Resorption, Orthodontic Wires and Alloys.
The authors tagged it with the keywords Alignment, Orthodontic archwire and Pain.
What This Means in Plain Language
The paper is a randomized and parallel-group study of Copper (Supplement).
Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2023 (International orthodontics), a journal based in France.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.