← Human Trials & Peer-Reviewed Studies

The effect of vitamin D supplementation on some metabolic parameters in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis of 8 RCTs.

Plain-language guide to PMID 37861495 (2023): meta-analysis of Vitamin D, K2, Magnesium and Zinc, fatty liver & elevated liver enzymes.

Key Facts

PMID
37861495
Journal
Medicine
Year
2023
Study type
Meta-Analysis
Authors
Chen X et al. (5 authors)
DOI
10.1097/MD.0000000000035717

What This Paper Covers, in Plain Language

What It Covers

The paper reports a study of Vitamin D, K2, Magnesium and Zinc in the context of fatty liver & elevated liver enzymes, published as a meta-analysis.

To systematically evaluate the effects of vitamin D supplementation in patients with nonalcoholic fatty liver disease (NAFLD).

Who the Included Studies Covered

Meta-analysis was conducted by using Review Manager 5.4 software after evaluating in terms of inclusion and exclusion criteria.

The outcome indicators include 25-hydroxyvitamin D [25(OH)D] levels, insulin resistance index (homeostasis model assessment of insulin resistance), fasting blood glucose, and fasting insulin levels (FINS).

How the Review Was Done

National Library of Medicine, Cochrane Library, Elsevier, China National Knowledge Infrastructure, Web of Science, WANFANG databases, and Google Scholar were retrieved to collect relevant randomized controlled trials, which are published from the earliest records the time the database was created to April 2023.

What Was Measured

To systematically evaluate the effects of vitamin D supplementation in patients with nonalcoholic fatty liver disease (NAFLD).

Topics PubMed links to this paper include Non-alcoholic Fatty Liver Disease, Insulin Resistance, Blood Glucose, Dietary Supplements, Vitamin D, Insulin and Randomized Controlled Trials as Topic.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc in people with fatty liver & elevated liver enzymes.

Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2023 (Medicine), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Fatty liver & elevated liver enzymes research.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.