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Zinc oxide-ozonated olive oil as a new root canal filling material in primary molars: a clinical randomized controlled trial.
Plain-language guide to PMID 37864602 (2023): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 37864602
- Journal
- Clinical oral investigations
- Year
- 2023
- Study type
- Randomized Controlled Trial
- Authors
- El-Desouky SS et al. (6 authors)
- DOI
- 10.1007/s00784-023-05329-z
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
The complex root canal anatomy of primary teeth keeps it very tricky to attain appropriate cleansing by biomechanical instrumentation, so obtaining an obturating material with excellent antimicrobial properties is a challenge in current clinical pulpectomy practice.
So, this study aimed to assess the clinical and radiographic performance of zinc oxide-ozonated olive oil as a primary root canal filling material.
Why It Was Studied
The intricate torturous primary root canal anatomy, in addition to the child's negative behavior, interferes with the complete debridement, so the long-lasting antibacterial effect of the primary root canal filling material aids in the pulpectomy success.
Who Took Part
The age groups tagged for this paper are young children and children.
Ninety non-vital primary molars in children ranging from 4 to 8 years were allocated into three groups in which root canals were filled with zinc oxide-ozonated olive oil, zinc oxide-olive oil, and zinc oxide-eugenol (ZOE) according to each group after pulpectomy procedure.
How the Study Was Run
The researchers set it up as a randomized study.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
Clinical and radiographic evaluations were done at 3-, 6-, and 12-month follow-up periods.
Statistical analysis was performed for the collected data.
What Was Measured
The intricate torturous primary root canal anatomy, in addition to the child's negative behavior, interferes with the complete debridement, so the long-lasting antibacterial effect of the primary root canal filling material aids in the pulpectomy success.
Topics PubMed links to this paper include Molar, Olive Oil, Pulpectomy, Root Canal Filling Materials, Tooth, Deciduous, Zinc Oxide and Zinc Oxide-Eugenol Cement.
Author keywords: Ozonated olive oil, Primary molars and Zinc-oxide eugenol.
What This Means in Plain Language
The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc.
The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2023 (Clinical oral investigations), a journal based in Germany.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.