Comparing Vitamin D Level Between Patients with Psoriasis and Healthy Individuals: A Systematic Review and Meta-Analysis.

What It Covers

Researchers studied Vitamin D, K2, Magnesium and Zinc in the context of psoriasis and psoriatic arthritis in this meta-analysis publication.

Psoriasis is nowadays regarded as a systemic inflammatory disorder.

Among the topicals, vitamin D derivates are often applied on the skin for their anti-inflammatory and immune-modulatory properties.

Who the Included Studies Covered

Quality assessment of studies was assessed using Newcastle Ottawa Checklist (NOS).

How the Review Was Done

The researchers searched in PubMed, Scopus, Web of Sciences, ScienceDirect and Science Information Database (SID) using the terms "Vitamin D" and "Psoriasis" including manuscripts in English, Italian and Persian.

Duplications were excluded using EndNote software and records were screened by title, abstract and full-text.

Heterogeneity indexes were evaluated using I2 and Q.

Sensitivity analysis and publication biases were also considered.

What Was Measured

Vitamin D serum levels in psoriasis (PsO) patients are still debated and an eventual depletion may offer the rational to integrate anti-psoriatic therapies with oral vitamin D.

Then, the researchers aimed to perform a systematic review and meta-analysis on the current evidence towards serum vitamin D level in PsO.

PubMed files the paper under topics including Vitamin D, Vitamins, Psoriasis and Vitamin D Deficiency.

The authors tagged it with the keywords meta-analysis, protective factor and serum vitamin D.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc in people with psoriasis and psoriatic arthritis.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2023 (Journal of evidence-based integrative medicine), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Psoriasis and psoriatic arthritis research.