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A microalgae docosahexaenoic acid supplement does not modify the influence of sex and diet on iron status in Spanish vegetarians or omnivores: A randomized placebo-controlled crossover study.

Plain-language guide to PMID 38042044 (2024): double-blind randomized controlled trial of Copper (Supplement).

Key Facts

PMID
38042044
Journal
Nutrition (Burbank, Los Angeles County, Calif.)
Year
2024
Study type
Randomized Controlled Trial
Authors
García-Maldonado E et al. (4 authors)
DOI
10.1016/j.nut.2023.112282

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Copper (Supplement).

Plant-based diets are accepted as healthy, provided that are well-planned and include supplements.

In this context, iron deficiency is a threat, and data from Spanish vegetarians are scarce.

The aim of this study was to determine if a microalgae ω-3 supplement rich in docosahexaenoic acid (DHA) affected iron status in this population.

Who Took Part

PubMed tags the participants as both men and women.

How the Study Was Run

The design is described as randomized, double-blind, placebo-controlled and crossover.

The participants were allocated by chance, so the Copper (Supplement) group and the comparison group should start out alike.

As a double-blind Copper (Supplement) study, the assignments were hidden from both participants and investigators until the end.

The comparison arm used a placebo, so changes seen with Copper (Supplement) could be set against what happens without it.

Each person switched between Copper (Supplement) and the comparison at some point, usually with a gap in between.

Iron biomarkers and nutrient intake (72-h dietary records) were analyzed in 204 usual consumers of lacto-ovo vegetarian (LOV), vegan (VEG), or omnivorous (OMN) diets.

What Was Measured

PubMed files the paper under topics including Docosahexaenoic Acids, Microalgae, Diet, Vegetarian, Iron, Diet, Vegetarians and Dietary Supplements.

Author keywords: Iron deficiency, Randomized controlled trial, Supplementation, Vegan and ω-3.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Copper (Supplement).

Results are reported in around 9 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2024 (Nutrition (Burbank, Los Angeles County, Calif.)), a journal based in United States.

More context: the Copper (Supplement) compound page, all human trials.

Our Notes on the Compound

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.