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Does vitamin D deficiency affect functional outcomes in hip fracture patients? A meta-analysis of cohort studies.

Plain-language guide to PMID 38112912 (2024): meta-analysis of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
38112912
Journal
Journal of endocrinological investigation
Year
2024
Study type
Meta-Analysis
Authors
Llombart R et al. (5 authors)
DOI
10.1007/s40618-023-02266-2

What This Paper Covers, in Plain Language

What It Covers

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a meta-analysis.

This study aimed to conduct a meta-analysis to quantify the effects of vitamin D deficiency on physical function and quality of life after hip fractures.

Why It Was Studied

Vitamin D deficiency is common in patients with hip fractures and may negatively affect functional recovery and quality of life (QOL).

Who the Included Studies Covered

The inclusion criteria were hip fracture, comparison between vitamin D deficiency and normal vitamin D levels in patients with hip fracture, and functional outcome as the primary outcome.

The exclusion criteria were case reports, reviews, duplicates, studies with a high risk of bias, and non-comparable or missing data.

How the Review Was Done

The PubMed, EMBASE, Scopus, and Cochrane Library databases were searched for relevant studies.

Two independent reviewers selected studies, extracted data, assessed bias, and performed meta-analyses using the Review Manager.

Heterogeneity and publication bias were also assessed.

Two independent reviewers selected the studies, extracted data, and assessed the risk of bias.

The researchers performed a meta-analysis using Review Manager and assessed heterogeneity and publication bias.

What Was Measured

Topics PubMed links to this paper include Vitamin D Deficiency, Hip Fractures, Quality of Life, Cohort Studies, Recovery of Function and Vitamin D.

The authors tagged it with the keywords Functional and Meta-analysis.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2024 (Journal of endocrinological investigation), a journal based in Italy.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.