Alignment efficiency and three-dimensional assessment of root resorption after alignment with conventional and copper-nickel-titanium archwires: A randomized controlled trial.

What Was Tested

Researchers studied Copper (Supplement) in this randomized controlled trial publication.

To compare alignment efficiency and root resorption between nickel-titanium (NiTi) and copper-nickel-titanium (CuNiTi) archwires after complete alignment in mandibular anterior region.

Mixed-factorial ANOVA was used to compare Little's Irregularity Index (LII).

Paired t-test was used to assess external apical root resorption (EARR) within groups, whereas independent t-test was used to evaluate LII and EARR between the groups.

Who Took Part

In this two-arm parallel single-blind randomized controlled trial, forty-four patients with Class I malocclusion with mandibular anterior crowding were recruited form orthodontic clinic of All India Institute of Medical Sciences (Jodhpur, India).

Patients were randomly allocated into NiTi and CuNiTi groups, with a 1:1 allocation.

How the Study Was Run

In design terms this was a randomized, single-blind and parallel-group study.

The participants were allocated by chance, so the Copper (Supplement) group and the comparison group should start out alike.

Only one side, usually the participants, was kept unaware of whether Copper (Supplement) was given.

Groups ran in parallel: each of the participants stayed in one arm throughout.

Alignment was performed using 0.014-in, 0.016-in, 0.018-in, 0.019x0.025-in archwire sequence in the respective groups, which terminated in 0.019 x 0.025-in stainless-steel working archwire.

The primary outcome was alignment efficiency, measured on study models from baseline (T0) to the first, second, third, fourth and fifth-month (T5).

Secondary outcome was root resorption, measured from CBCT scans taken at T0 and T5.

For assessing the proportion of patients with complete alignment at the end of each month, Kaplan-Meier survival curve was built and time to treatment completion was compared between groups using log rank test.

What Was Measured

PubMed files the paper under topics including Root Resorption, Copper, Nickel, Titanium and Tooth Resorption.

What This Means in Plain Language

The paper is a randomized, single-blind and parallel-group study of Copper (Supplement).

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2024 (Dental press journal of orthodontics), a journal based in Brazil.

More context: the Copper (Supplement) compound page, all human trials.