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Vitamin D Supplementation and Cardiovascular Disease Risks in More Than 134000 Individuals in 29 Randomized Clinical Trials and 157000 Individuals in 30 Prospective Cohort Studies: An Updated Systematic Review and Meta-analysis.

Plain-language guide to PMID 38315909 (2023): meta-analysis of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
38315909
Journal
Journal of research in health sciences
Year
2023
Study type
Meta-Analysis
Authors
Rasouli MA et al. (6 authors)
DOI
10.34172/jrhs.2023.129

What This Paper Covers, in Plain Language

What It Covers

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a meta-analysis.

This systematic review aimed to assess the effect of vitamin D supplements on CVDs considering cohort studies and clinical trials.

Why It Was Studied

According to the findings from observational studies and clinical trials assessing the effect of vitamin D supplements on cardiovascular diseases (CVDs), there are still contradictory results.

Study Design: A systematic review.

Who the Included Studies Covered

PubMed indexes the participants as middle-aged adults, both men and women.

How the Review Was Done

MEDLINE/PubMed, Science Direct, Embase, and Cochrane Library databases were reviewed by two reviewers independently until 2022.

Then, Stata version 14 was used for statistical analysis.

What Was Measured

According to the findings from observational studies and clinical trials assessing the effect of vitamin D supplements on cardiovascular diseases (CVDs), there are still contradictory results.

PubMed files the paper under topics including Cardiovascular Diseases, Vitamin D, Dietary Supplements, Randomized Controlled Trials as Topic, Incidence, Vitamin D Deficiency and Vitamins.

The authors tagged it with the keywords Meta-analysis, Prospective cohort study and Randomized clinical trials.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2023 (Journal of research in health sciences), a journal based in Iran.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.