Comparative Analysis of the Efficacy of Intrathecal Fentanyl and Magnesium Sulphate as an Adjuvant to Bupivacaine: A Double-Blinded Randomized Controlled Trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

The duration and potency of the subarachnoid block (SAB) can be enhanced by incorporating spinal additives into local anesthetics.

Who Took Part

The study group was 100 patients.

After authorization of ethical committee, 100 patients belonging to American Society of Anesthesiologists grades I and II, were chosen and split into two groups with 50 patients each.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Blinding on both sides kept the patients and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

Perioperative circulatory parameters and sensory and motor block features are noted and compared.

Version 21.0 of Statistical Package for the Social for Windows was used for all statistical calculations.

What Was Measured

The subject headings attached to it are Adjuvants, Immunologic, Analgesics, Opioid, Anesthetics, Local, Bupivacaine, Fentanyl, Injections, Spinal and Magnesium Sulfate.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 100 patients.

Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2023 (Asian journal of anesthesiology), a journal based in China (Republic : 1949- ).

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.