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Effect of treatment with growth hormone on body composition and metabolic profile of short children born small for gestational age.

Plain-language guide to PMID 38359318 (2024): clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Key Facts

PMID
38359318
Journal
Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo
Year
2024
Study type
Clinical Trial
Authors
Kühl AM et al. (3 authors)
DOI
10.1590/1984-0462/2024/42/2023073

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over), published as a clinical trial.

Who Took Part

The age groups tagged for this paper are infants and children, both men and women.

Children born SGA, with birth weight and/or length <-2 standard deviations (SD) for gestational age and sex, prepubertal, born at full term, of both genders, with the indication for treatment with rGH were included.

How the Study Was Run

It is a clinical, non-randomized, and paired study.

Total lean mass (LM) and total fat mass (FM) were carried out using dual-energy X-ray absorptiometry (DXA), and the metabolic profile was assessed for insulin, glycemia, IGF-1 levels and lipid profile.

What Was Measured

The subject headings attached to it are Growth Hormone, Gestational Age, Human Growth Hormone, Body Composition, Metabolome, Cholesterol and Body Height.

What This Means in Plain Language

This is a clinical trial of Exogenous HGH, sermorelin & older GHRPs (why they're passed over).

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2024 (Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo), a journal based in Brazil.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.

Our Notes on the Compound

Exogenous HGH, sermorelin & older GHRPs (why they're passed over): Constant levels suppress the body's own GHRH, raise somatostatin and dull pituitary response.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.