An 8-Week Vitamin D3-Fortified Fruit Drink Supplementation Increases Serum Ferritin Concentration: A Randomized Controlled Trial in Malaysian Women With Low Iron Stores.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

There is limited randomized controlled trial evidence to support the association between vitamin D deficiency and anemia risk, highlighting the necessity for further investigations into the role of vitamin D in influencing iron status.

A mixed model, repeated measures analysis of variance was used to analyze the intervention effect.

Who Took Part

By PubMed's age tags, the people studied were teenagers, young adults and adults, women only.

A total of 45 healthy, nonpregnant, nonlactating subjects aged 18 through 40 years (mean [SD] 25.3 [4.6] years) were included in the study, excluding those who donated blood 6 months prior, regularly consumed nutritional supplements, or had gastrointestinal or iron metabolic disorders.

Subjects were randomly assigned to receive either vitamin D3-fortified fruit drink or a placebo.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

An 8-week double-blind randomized controlled trial was conducted.

What Was Measured

A mixed model, repeated measures analysis of variance was used to analyze the intervention effect.

The subject headings attached to it are Ferritins, Cholecalciferol, Food, Fortified, Dietary Supplements, Malaysia, Vitamin D and Anemia, Iron-Deficiency.

Author keywords: Iron status, Iron stores, Iron-deficient women, Vitamin D3 supplementation and Vitamin D3–fortified fruit drink.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2024 (Journal of the Academy of Nutrition and Dietetics), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.