Zinc Supplementation Initiated Prior to or During Pregnancy Modestly Impacted Maternal Status and High Prevalence of Hypozincemia in Pregnancy and Lactation: The Women First Preconception Maternal Nutrition Trial.

Plain-language guide to PMID 38621624 (2024): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 100 women.

Key Facts

PMID: 38621624
Journal: The Journal of nutrition
Year: 2024
Study type: Randomized Controlled Trial
Authors: Kemp JF et al. (12 authors)
DOI: 10.1016/j.tjnut.2024.04.018
Registered trial: NCT01883193

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

The objectives of this study were to evaluate the effect of preconception compared with prenatal zinc supplementation (compared with control) on maternal SZC and hypozincemia during pregnancy and early lactation in women in low-resource settings, and assess associations with birth anthropometry.

Why It Was Studied

Data regarding effects of small-quantity-lipid-based nutrient supplements (SQ-LNS) on maternal serum zinc concentrations (SZC) in pregnancy and lactation are limited.

Who Took Part

The study group was 100 women.

By PubMed's age tags, the people studied were young adults and adults, women only.

How the Study Was Run

The researchers set it up as a randomized study.

The women were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Birth anthropometry was examined for newborns with ultrasound-determined gestational age.

Statistical analyses were performed separately for each time point.

What Was Measured

The subject headings attached to it are Zinc, Dietary Supplements, Lactation, Maternal Nutritional Physiological Phenomena, Prevalence, Pregnancy Complications and India.

Author keywords: birth length, birth weight, inflammation, small-quantity lipid-based nutrient supplement (SQ-LNS) and zinc deficiency.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 100 women.

Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2024 (The Journal of nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Vitamin D, K2, Magnesium and Zinc in the library

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.