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Vitamin D status of pregnant women with obesity in the UK and its association with pregnancy outcomes: a secondary analysis of the UK Pregnancies Better Eating and Activity Trial (UPBEAT) study.

Plain-language guide to PMID 38634258 (2024): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 1089 participants.

Key Facts

PMID
38634258
Journal
The British journal of nutrition
Year
2024
Study type
Randomized Controlled Trial
Authors
O'Callaghan KM et al. (8 authors)
DOI
10.1017/S0007114524000862

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Prenatal vitamin D deficiency is widely reported and may affect perinatal outcomes.

In this secondary analysis of the UK Pregnancies Better Eating and Activity Trial, the researchers examined vitamin D status and its relationship with selected pregnancy outcomes in women with obesity (BMI ≥ 30 kg/m2) from multi-ethnic inner-city settings in the UK.

Who Took Part

The study group was 1089 participants.

PubMed indexes the participants as young adults and adults, women only.

How the Study Was Run

The design is described as randomized.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Determinants of vitamin D status at a mean of 17 ± 1 weeks' gestation were assessed using multivariable linear regression and reported as percent differences in serum 25-hydroxyvitamin D (25(OH)D).

What Was Measured

Prenatal vitamin D deficiency is widely reported and may affect perinatal outcomes.

In this secondary analysis of the UK Pregnancies Better Eating and Activity Trial, the researchers examined vitamin D status and its relationship with selected pregnancy outcomes in women with obesity (BMI ≥ 30 kg/m2) from multi-ethnic inner-city settings in the UK.

The subject headings attached to it are Vitamin D Deficiency, United Kingdom, Vitamin D, Obesity, Pregnancy Outcome, Pregnancy Complications and Nutritional Status.

The authors tagged it with the keywords 25-hydroxyvitamin D, Gestational diabetes, High BMI, Hyperglycaemia, Perinatal health and Pregnancy outcomes.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 1089 participants.

With several hundred people or more, it is a fairly large study for this kind of research.

The publication is from 2024 (The British journal of nutrition), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.