Role of preoperative zinc, magnesium and budesonide gargles in Postoperative Sore Throat (POST) - a randomised control trial.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

CTRI/2021/05/033741 Date-24/05/2021(Clinical Trial Registry of India).

Who Took Part

The abstract describes 180 patients taking part.

PubMed indexes the participants as young adults, adults and middle-aged adults, both men and women.

The researchers conducted a prospective, randomized, double-blind, controlled equivalence trial in 180 patients admitted for elective surgical procedures under general anaesthesia.

Sore throat assessment and haemodynamic recording was done postoperatively at immediate recovery (0 h) and 2, 4, 6, 8, 12 and 24 h post-operatively.

How the Study Was Run

The design is described as randomized and double-blind.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

POST was graded on a four-point scale (0-3).

What Was Measured

The subject headings attached to it are Pharyngitis, Budesonide, Postoperative Complications, Preoperative Care, Zinc, Magnesium Sulfate and Intubation, Intratracheal.

The authors tagged it with the keywords Endotracheal intubation, General Anaesthesia, Post-operative and Sore throat.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 180 patients.

Results are reported in around 8 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2024 (BMC anesthesiology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.