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Hepatic Decompensation in Patients with Chronic Liver Disease: Exploring the Role of Vitamin D Deficiency as a Prognostic Marker.
Plain-language guide to PMID 38736123 (2024): observational study of Vitamin D, K2, Magnesium and Zinc in 100 patients.
Key Facts
- PMID
- 38736123
- Journal
- The Journal of the Association of Physicians of India
- Year
- 2024
- Study type
- Observational Study
- Authors
- Nilajkar GM et al. (3 authors)
- DOI
- 10.59556/japi.72.0352
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as an observational study.
To analyze the link between levels of vitamin D and decompensation of liver cirrhosis.
Why It Was Studied
It is estimated that one-third of liver cirrhosis patients are vitamin D deficient.
It has been reported that as liver disease progresses, the incidence of vitamin D deficiency rises.
Who Took Part
The abstract describes 100 patients taking part.
The age groups tagged for this paper are adults and middle-aged adults, both men and women.
This observational, cross-sectional study was conducted on 100 patients with liver cirrhosis admitted at Goa Medical College, a tertiary care government hospital in Goa, from March 2020 to February 2022.
Child-Pugh (CP) and Model for End-Stage Liver Disease (MELD) scores were calculated, and based on these, patients were grouped into classes of disease severity.
How the Study Was Run
Demographic profile, history, and examination findings were recorded, and biochemical analysis included vitamin D levels.
Data was interpreted using Statistical Package for the Social Sciences (SPSS) version 22.
What Was Measured
Several clinical implications of vitamin D levels have been proposed, including as a prognostic marker for the assessment of mortality in liver cirrhosis.
The subject headings attached to it are Vitamin D Deficiency, Cross-Sectional Studies, Prognosis, Liver Cirrhosis, Biomarkers and Vitamin D.
What This Means in Plain Language
This is an observational study of Vitamin D, K2, Magnesium and Zinc in 100 patients.
Results are reported in around 7 sentences of the abstract; we leave them to the paper itself rather than summarise them.
The publication is from 2024 (The Journal of the Association of Physicians of India), a journal based in India.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.