Implications of maternal vitamin D administration for the neonatal respiratory distress syndrome: A randomized clinical trial.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

This study aimed to evaluate the effect of 25 (OH) D administrations in pregnant women with findings of preterm labor on the incidence of RDS in their preterm neonates.

Who Took Part

According to the abstract, 175 subjects were involved.

The age groups tagged for this paper are adults, women only.

How the Study Was Run

The researchers set it up as a randomized study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Serum concentrations of 25(OH) D were measured shortly after birth in both mothers and neonates.

Then, clinical and laboratory results of mothers and their offspring were recorded (in a checklist).

Short-term outcomes and the need for respiratory support were also assessed.

Data were analyzed by independent t-test, Mann-Whitney U test, Fisher's exact test, and chi-square test.

What Was Measured

The subject headings attached to it are Respiratory Distress Syndrome, Newborn, Vitamin D, Vitamin D Deficiency, Infant, Premature, Gestational Age and Obstetric Labor, Premature.

Author keywords: 25(OH) D, Mother, neonate, premature infant, prematurity and preterm.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 175 subjects.

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2024 (Journal of neonatal-perinatal medicine), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.