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Effects of vitamin D in pregnancy on maternal and offspring health-related outcomes: An umbrella review of systematic review and meta-analyses.
Plain-language guide to PMID 38816412 (2024): systematic review of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 38816412
- Journal
- Nutrition & diabetes
- Year
- 2024
- Study type
- Systematic Review
- Authors
- Chien MC et al. (5 authors)
- DOI
- 10.1038/s41387-024-00296-0
What This Paper Covers, in Plain Language
What It Covers
Researchers studied Vitamin D, K2, Magnesium and Zinc in this systematic review publication.
To summarize systematic reviews and meta-analyses evaluating the effects of vitamin D deficiency and of vitamin D supplementation in pregnancy on maternal and offspring health-related outcomes.
The quality of the included articles' methodology was assessed using AMSTAR 2 (A Measurement Tool to Assess Systematic Reviews-2).
Why It Was Studied
Vitamin D deficiency has been linked with several adverse maternal and fetal outcomes.
Two reviewers independently chose studies and collected information on health outcomes.
Who the Included Studies Covered
PubMed tags the participants as women only.
How the Review Was Done
Prior to conducting this umbrella review, the researchers registered the protocol in PROSPERO (CRD42022368003).
The researchers conducted searches in PubMed, Embase, and Cochrane Library for systematic reviews and meta-analyses on vitamin D in pregnancy, from database inception to October 2, 2023.
All outcomes related to vitamin D in pregnancy obtained from the systematic reviews and meta-analyses were extracted.
What Was Measured
Vitamin D deficiency has been linked with several adverse maternal and fetal outcomes.
Two reviewers independently chose studies and collected information on health outcomes.
PubMed files the paper under topics including Vitamin D Deficiency, Vitamin D, Pregnancy Complications, Dietary Supplements, Pregnancy Outcome, Systematic Reviews as Topic and Meta-Analysis as Topic.
What This Means in Plain Language
This is a systematic review of Vitamin D, K2, Magnesium and Zinc.
The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2024 (Nutrition & diabetes), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.