Efficacy of Oral Magnesium on Bone Regeneration and Implant Stability in Immediate Dental Implants: A Randomized Controlled Trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

To assess the impact of magnesium on osseointegration by examining various aspects of implant stability, correlating them with serum bone markers, and establishing a foundation for future research on its potential as a potent analgesic.

Who Took Part

The study group was 54 patients.

The age groups tagged for this paper are adults and middle-aged adults, both men and women.

A total of 54 patients were recruited.

Immediate implant placement was performed after the extraction of the indicated mandibular molar teeth, and the patients were divided into two groups of 27 patients each: (1) placebo-lactose (control group) and (2) magnesium citrate (intervention group).

How the Study Was Run

The design is described as randomized and placebo-controlled.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

Bone growth in the peri-implant area was assessed radiographically immediately after the operation, at 6 weeks, and at 12 weeks.

Implant stability was measured immediately after the operation, at 4 weeks, and at 12 weeks.

What Was Measured

PubMed files the paper under topics including Alkaline Phosphatase, Bone Regeneration, Dental Implants, Immediate Dental Implant Loading, Magnesium, Mandible and Osseointegration.

The authors tagged it with the keywords analgesia, immediate implant, implant stability quotient and magnesium citrate.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 54 patients.

Results are reported in around 11 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2025 (The International journal of oral & maxillofacial implants), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.