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An Examination into the Effects of a Nutraceutical Supplement on Cognition, Stress, Eye Health, and Skin Satisfaction in Adults with Self-Reported Cognitive Complaints: A Randomized, Double-Blind, Placebo-Controlled Trial.
Plain-language guide to PMID 38892705 (2024): double-blind randomized controlled trial of Copper (Supplement).
Key Facts
- PMID
- 38892705
- Journal
- Nutrients
- Year
- 2024
- Study type
- Randomized Controlled Trial
- Authors
- Lopresti AL et al. (8 authors)
- DOI
- 10.3390/nu16111770
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Copper (Supplement), published as a randomized controlled trial.
Therefore, this double-blind, randomized, placebo-controlled study aimed to investigate the effects of a nutritional supplement on changes in cognitive performance.
Why It Was Studied
The primary outcomes comprised changes in cognitive tasks assessing episodic memory, working memory, and verbal memory.
Secondary and exploratory measures included changes in the speed of information processing, attention, and self-report measures of memory, stress, and eye and skin health.
Who Took Part
PubMed indexes the participants as adults, middle-aged adults and older adults, both men and women.
How the Study Was Run
The design is described as randomized, double-blind and placebo-controlled.
The participants were allocated by chance, so the Copper (Supplement) group and the comparison group should start out alike.
Blinding on both sides kept the participants and researchers unaware of who received Copper (Supplement).
A placebo (an inactive look-alike) gave the Copper (Supplement) group a baseline to be compared against.
Moreover, changes in plasma concentrations of brain-derived neurotrophic factor, malondialdehyde, tumor-necrosis factor-α, and interleukin-6 were measured, along with changes in skin carotenoid concentrations.
What Was Measured
The primary outcomes comprised changes in cognitive tasks assessing episodic memory, working memory, and verbal memory.
Secondary and exploratory measures included changes in the speed of information processing, attention, and self-report measures of memory, stress, and eye and skin health.
PubMed files the paper under topics including Dietary Supplements, Cognition, Brain-Derived Neurotrophic Factor, Vitamin E, Xanthophylls, Skin and Antioxidants.
Author keywords: astaxanthin, carotenoids, grapes, memory and nutrients.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Copper (Supplement).
The publication is from 2024 (Nutrients), a journal based in Switzerland.
More context: the Copper (Supplement) compound page, all human trials.
Our Notes on the Compound
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.