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Serum vitamin D, blood pressure and hypertension risk in the HUNT study using observational and Mendelian randomization approaches.

Plain-language guide to PMID 38906907 (2024): observational study of Vitamin D, K2, Magnesium and Zinc, low blood pressure and orthostatic hypotension.

Key Facts

PMID
38906907
Journal
Scientific reports
Year
2024
Study type
Observational Study
Authors
Jiang L et al. (8 authors)
DOI
10.1038/s41598-024-64649-6

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in the context of low blood pressure and orthostatic hypotension in this observational study publication.

Limited studies have triangulated the relationship between serum 25-hydroxyvitamin D [25(OH)D] levels and systolic blood pressure (SBP), diastolic blood pressure (DBP) or hypertension risk utilizing both observational and Mendelian randomization (MR) approaches.

The researchers employed data from the Norwegian Trøndelag Health Study (HUNT) to conduct cross-sectional (n = 5854) and prospective (n = 3592) analyses, as well as one-sample MR (n = 86,324).

Who Took Part

PubMed indexes the participants as adults, middle-aged adults and older adults, both men and women.

What Was Measured

Limited studies have triangulated the relationship between serum 25-hydroxyvitamin D [25(OH)D] levels and systolic blood pressure (SBP), diastolic blood pressure (DBP) or hypertension risk utilizing both observational and Mendelian randomization (MR) approaches.

PubMed files the paper under topics including Vitamin D, Mendelian Randomization Analysis, Hypertension, Blood Pressure, Cross-Sectional Studies, Norway and Risk Factors.

The authors tagged it with the keywords Observational analyses, Serum 25-hydroxyvitamin D and The HUNT Study.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in people with low blood pressure and orthostatic hypotension.

The publication is from 2024 (Scientific reports), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Low blood pressure and orthostatic hypotension research.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.