Evaluation of vitamin D in the diagnosis of infants with respiratory distress, the clinical value: A systematic review and meta-analysis.

What It Covers

Researchers studied Vitamin D, K2, Magnesium and Zinc in this meta-analysis publication.

The purpose of the present study is a systematic review and meta-analysis to evaluate the correlation between serum levels of Vit.

D in mothers and newborns with RD, and to determine the impact of treating either population on the clinical outcomes of afflicted infants.

To assess potential publication bias, a funnel plot was generated and Egger's regression test was applied, utilizing a random-effects model.

Why It Was Studied

Respiratory distress (RD) is the most common cause of admission to the Neonatal Intensive Care Unit (NICU).

The role of Vitamin D in the development and fortification of fetal pulmonary architecture and the synthesis of surfactants is well-documented.

Who the Included Studies Covered

PubMed tags the participants as women only.

A comprehensive literature search was conducted across various databases, including PubMed, ScienceDirect, Cochrane Library, ISI, and Google Scholar, using a combination of keywords such as RD, diagnosis, vitamin D, mothers, infants, vitamin D supplementation, Respiratory distress syndrome(RDS), and Transient Tachypnea of Newborn (TTN).

How the Review Was Done

D levels in newborns and their mothers and the likelihood of RD, RDS and TTN in infants.

What Was Measured

Topics PubMed links to this paper include Respiratory Distress Syndrome, Newborn, Vitamin D, Vitamin D Deficiency and Transient Tachypnea of the Newborn.

Author keywords: Diagnosis, Infants, Mothers, Serum level of vitamin D and Transient Tachypnea of Newborn.

What This Means in Plain Language

This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 12 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2025 (Paediatric respiratory reviews), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.