Exploring the association between serum Vitamin D levels and the development of coronary artery lesions in Kawasaki disease - a systematic review.

What It Covers

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a systematic review.

Kawasaki Disease (KD) involves arterial inflammation, primarily affecting the coronary arteries and leading to coronary artery lesions.

Recent advancements in understanding the immunomodulatory roles of vitamin D have prompted investigations into the potential correlation between serum vitamin D levels and the risk of coronary artery lesions (CAL) in KD.

How the Review Was Done

A systematic search utilizing relevant keywords related to Kawasaki disease and coronary artery lesions was conducted across four databases (PubMed, Embase, Scopus, and Web of Science).

The quality of the incorporated studies was assessed utilizing the Newcastle-Ottawa Scale.

The study protocol is registered in PROSPERO under the registry code CRD42024493204.

What Was Measured

Recent advancements in understanding the immunomodulatory roles of vitamin D have prompted investigations into the potential correlation between serum vitamin D levels and the risk of coronary artery lesions (CAL) in KD.

The subject headings attached to it are Mucocutaneous Lymph Node Syndrome, Vitamin D and Coronary Artery Disease.

The authors tagged it with the keywords Coronary artery aneurysm, Coronary artery lesion, Kawasaki disease and Systematic review.

What This Means in Plain Language

This is a systematic review of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2024 (Pediatric rheumatology online journal), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.