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Efficacy and Tolerability of a Food Supplement Based on Zea mays L., Gymnema sylvestre (Retz.) R.br.ex Sm, Zinc and Chromium for the Maintenance of Normal Carbohydrate Metabolism: A Monocentric, Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Plain-language guide to PMID 39125340 (2024): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in 81 individuals.
Key Facts
- PMID
- 39125340
- Journal
- Nutrients
- Year
- 2024
- Study type
- Randomized Controlled Trial
- Authors
- Buccato DG et al. (13 authors)
- DOI
- 10.3390/nu16152459
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in this randomized controlled trial publication.
Who Took Part
The abstract describes 81 individuals taking part.
The age groups tagged for this paper are teenagers, young adults, adults, middle-aged adults and older adults, both men and women.
The subjects were randomized into three groups (27 in each group) and supplemented with one or two tablet(s)/day of FS (groups 1 and 2, respectively), or two tablets/day of placebo (group 3).
How the Study Was Run
In design terms this was a randomized, double-blind and placebo-controlled study.
The individuals were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
Blinding on both sides kept the individuals and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.
A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.
What Was Measured
Topics PubMed links to this paper include Zea mays, Dietary Supplements, Zinc, Chromium, Blood Glucose, Gymnema sylvestre and Plant Extracts.
Author keywords: essential microelements, food supplement, glucose metabolism and vegetable extracts.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in 81 individuals.
The publication is from 2024 (Nutrients), a journal based in Switzerland.
More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.
Our Notes on the Compounds
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.