Vitamin B12 Status in Vegan and Vegetarian Seventh-Day Adventists: A Systematic Review and Meta-Analysis of Serum Levels and Dietary Intake.

What It Covers

This meta-analysis looks at Cyanocobalamin (Vitamin B12).

This systematic review and meta-analysis aimed to evaluate the vitamin B12 status and intake of Seventh-day Adventists following a plant-based diet and compare it with omnivore controls to investigate their susceptibility for vitamin B12 deficiency.

Sensitivity analysis was performed using the 'leave-on-out' method to assess individual study influence on overall effect size and heterogeneity.

Why It Was Studied

Peer-reviewed articles were identified through a comprehensive search in PubMed, Scopus, and Google Scholar databases from inception up to the year 2024 using specific keywords related to vitamin B12 and Seventh-day Adventists.

Studies that did not present distinguishable results for vegetarian/vegan from omnivore Adventists or only reported on food item intake without specific vitamin B12 data were excluded.

Who the Included Studies Covered

PubMed tags the participants as women only.

How the Review Was Done

Observational studies published in the English language were included if they reported on vitamin B12 status or intake among plant-based Adventists and compared it with omnivore controls who may or may not have been Adventists.

What Was Measured

Two independent reviewers extracted data on study characteristics, vitamin B12 intake, and serum levels using a customised data extraction form, resolving discrepancies through consultation with a third reviewer.

The subject headings attached to it are Vitamin B 12, Vitamin B 12 Deficiency, Diet, Vegetarian, Vegetarians, Vegans, Diet, Vegan and Protestantism.

Author keywords: adventist and vitamin B12.

What This Means in Plain Language

This is a meta-analysis of Cyanocobalamin (Vitamin B12).

Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2025 (American journal of health promotion : AJHP), a journal based in United States.

More context: the Cyanocobalamin (Vitamin B12) compound page, all human trials.