The role of IGF1 in determining body composition in children and adolescents with growth hormone deficiency and those with idiopathic short stature.

What Was Tested

Researchers studied IGF-1 LR3 and Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in this observational study publication.

The researchers aimed to investigate the relationship between IGF1 level and body composition in children and adolescents undergoing rhGH therapy for growth hormone deficiency (GHD) and idiopathic short stature (ISS).

Who Took Part

The study group was 135 patients.

PubMed indexes the participants as young children, children and teenagers, both men and women.

This observational retrospective study included the bioimpedance analysis (BIA) reports (n = 305) of 135 pediatric patients (age 5-18 years), 64 with GHD and 71 with ISS, conducted as part of routine clinic visits.

How the Study Was Run

Sociodemographic and clinical data were extracted from medical records.

What Was Measured

The subject headings attached to it are Body Composition, Insulin-Like Growth Factor I, Human Growth Hormone, Growth Disorders, Dwarfism, Pituitary and Body Mass Index.

Author keywords: bioelectrical impedance analysis (BIA), fat percentage, muscle mass, muscle-to-fat ratio, pediatric patients and sex dimorphism.

What This Means in Plain Language

This is an observational study of IGF-1 LR3 and Exogenous HGH, sermorelin & older GHRPs (why they're passed over) in 135 patients.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2024 (Endocrine), a journal based in United States.

More context: the IGF-1 LR3 compound page and the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page, all human trials.