Multicentric Post-marketing Surveillance (PMS) Observational Study of Ascorbic Acid and Zinc Effervescent Tablets in Indian Patients with Vitamin C and Zinc Deficiency.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this observational study publication.

The objective of this Multicentric Post-Marketing Surveillance (PMS) study was to evaluate the safety and tolerance of vitamin C and zinc tablets in the Indian population experiencing deficiencies of these nutrients.

Furthermore, the study aimed to provide insights into physicians' prescription practices and characterise the patient population receiving the study medication.

The primary aim was to evaluate the safety and tolerability of zinc and ascorbic acid effervescent tablets for those who were deficient in zinc and vitamin C.

Who Took Part

The abstract describes 358 participants taking part.

The age groups tagged for this paper are teenagers, young adults, adults, middle-aged adults and older adults, both men and women.

This prospective observational study involved 358 participants from 8 study sites across India (including 2 government hospital sites), spanning a duration of approximately 12 weeks (3 months).

The analysis included evaluating the incidence, percentage, and correlation of adverse events with the treatment (safety population).

How the Study Was Run

The design is described as multicenter.

More than one site took part, so the participants came from several places.

Throughout the study period, adverse events were monitored and categorised by MedDRA Primary System Organ Class and Preferred Term.

Additionally, the frequencies of adverse drug reactions were examined across all enrolled patients.

Vital signs and symptom-focused physical examinations were conducted during each visit in the safety population.

What Was Measured

The subject headings attached to it are Ascorbic Acid, Product Surveillance, Postmarketing, India, Zinc, Tablets and Ascorbic Acid Deficiency.

Author keywords: adverse drug reactions, effervescent tablets, post-marketing surveillance, vitamin C and vitamin deficiency.

What This Means in Plain Language

The paper is a multicenter study of Vitamin D, K2, Magnesium and Zinc in 358 participants.

With several hundred people or more, it is a fairly large study for this kind of research.

Its findings take up roughly 10 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2025 (Reviews on recent clinical trials), a journal based in United Arab Emirates.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.