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The Temporal Change in Ionised Calcium, Parathyroid Hormone and Bone Metabolism Following Ingestion of a Plant-Sourced Marine Mineral + Protein Isolate in Healthy Young Adults
Plain-language guide to PMID 39339710 (2024): crossover randomized controlled trial study of Parathyroid Hormone (PTH 1-84).
Key Facts
- PMID
- 39339710
- Journal
- Nutrients
- Year
- 2024
- Study type
- Randomized Controlled Trial
- Authors
- Kozior M et al. (5 authors)
- DOI
- 10.3390/nu16183110
What This Study Did, in Plain Language
What Was Tested
Researchers studied Parathyroid Hormone (PTH 1-84) in this randomized controlled trial publication.
PS dietary minerals and proteins have bioactive properties that can affect bone health and the risk of fracture.
Methods: In a group randomised, cross-over design, this study evaluated the post-ingestion temporal pattern of change in arterialised ionised calcium (iCa), parathyroid hormone (PTH), C-terminal crosslinked telopeptide of type I collagen (CTX) and procollagen type 1 amino-terminal propeptide (P1NP) for 4 h following ingestion of a novel supplement (SUPP) containing a PS marine multi-mineral + PS protein isolate.
Who Took Part
PubMed indexes the participants as young adults and adults, both men and women.
How the Study Was Run
In design terms this was a randomized and crossover study.
The participants were allocated by chance, so the Parathyroid Hormone (PTH 1-84) group and the comparison group should start out alike.
In the crossover set-up each of the participants took both Parathyroid Hormone (PTH 1-84) and the comparison in turn, acting as their own control.
What Was Measured
Methods: In a group randomised, cross-over design, this study evaluated the post-ingestion temporal pattern of change in arterialised ionised calcium (iCa), parathyroid hormone (PTH), C-terminal crosslinked telopeptide of type I collagen (CTX) and procollagen type 1 amino-terminal propeptide (P1NP) for 4 h following ingestion of a novel supplement (SUPP) containing a PS marine multi-mineral + PS protein isolate.
PubMed files the paper under topics including Parathyroid Hormone, Calcium, Bone and Bones, Dietary Supplements, Collagen Type I, Procollagen and Minerals.
The authors tagged it with the keywords bone health, plant mineral, plant protein, post-prandial, sustainable diet and young adults.
What This Means in Plain Language
The paper is a randomized and crossover study of Parathyroid Hormone (PTH 1-84).
The publication is from 2024 (Nutrients), a journal based in Switzerland.
More context: the Parathyroid Hormone (PTH 1-84) compound page, all human trials.
Our Notes on the Compound
Parathyroid Hormone (PTH 1-84): The 84-amino-acid hormone that raises blood calcium; full-length PTH (Natpara) has been used in hypoparathyroidism. Teriparatide is its 1-34 fragment.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.